@codinghorror @GeePawHill I don't really know what you're talking about getting on a call about. also unclear why "scientific sounding" is a weasel word - i was using it specifically to describe the writing style of the bot, it's a pretty normal phrase to use.

endocannibinoid research is a pretty young field, relatively speaking, particularly endogenous endocannibinoids. it really only started taking off in the early 2010s for basic, mechanistic research - previously it was mostly epidemiology and gene/behavior correlates, and that hasn't yet percolated over into the clinic as far as i know, but i only have one eCB friend. it's not really all that surprising that there isn't a ton of specific mechanistic research about why THC may be ineffective in some poeple, but it does look like you've found the FAAH and the metabolism papers, those and papers on the CB1 receptor are all i know of.

like i said, i agree it sucks that doctors are frequently dismissive, and i also understand why that would make you turn to an LLM. also like i said the LLM can be a good way to find your way into the relevant research by following its links. the only thing i was saying is to be careful with falling down the rabbit hole - the LLM may be ok as a way to find paper, but once it starts prescribing things for you, you may want to have outside opinions handy.